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SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing.

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Title: SIRT1 affects DNA methylation of polycomb group protein target genes, a hotspot of the epigenetic shift observed in ageing.
Authors: Wakeling LA; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. luisa.wakeling@ncl.ac.uk., Ions LJ; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. Laura.Ions@nuth.nhs.uk., Escolme SM; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. s.m.escolme@ncl.ac.uk., Cockell SJ; Faculty of Medical Sciences, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. simon.cockell@ncl.ac.uk., Su T; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. t.su2@newcastle.ac.uk., Dey M; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. m.dey@ncl.ac.uk., Hampton EV; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. emilyhampton5@gmail.com., Jenkins G; Unilever R&D, Colworth Discover, Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK. gail.jenkins@unilever.com., Wainwright LJ; Unilever R&D, Colworth Discover, Colworth Science Park, Sharnbrook, Bedfordshire, MK44 1LQ, UK. linda.wainwright@unilever.com., McKay JA; Institute of Health and Society, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. jill.mckay@ncl.ac.uk., Ford D; Institute for Cell and Molecular Biosciences, Human Nutrition Research Centre, Newcastle University Medical School, Newcastle upon Tyne, NE2 4HH, UK. dianne.ford@ncl.ac.uk.
Source: Human genomics [Hum Genomics] 2015 Jun 24; Vol. 9, pp. 14. Date of Electronic Publication: 2015 Jun 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101202210 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-7364 (Electronic) Linking ISSN: 14739542 NLM ISO Abbreviation: Hum Genomics Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1479-7364
DOI:10.1186/s40246-015-0036-0