Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α.
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| Title: | Oncogenic mutations weaken the interactions that stabilize the p110α-p85α heterodimer in phosphatidylinositol 3-kinase α. |
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| Authors: | Echeverria I; Department of Bioengineering and Therapeutic Sciences, School of Pharmacy, University of California at San Francisco, CA, USA.; Department of Pharmaceutical Chemistry, School of Pharmacy, University of California at San Francisco, CA, USA.; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Gabelli SB; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Departments of Medicine and Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Amzel LM; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA. |
| Source: | The FEBS journal [FEBS J] 2015 Sep; Vol. 282 (18), pp. 3528-42. Date of Electronic Publication: 2015 Jul 24. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: Published by Blackwell Pub. on behalf of the Federation of European Biochemical Societies Country of Publication: England NLM ID: 101229646 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1742-4658 (Electronic) Linking ISSN: 1742464X NLM ISO Abbreviation: FEBS J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1742-4658 |
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| DOI: | 10.1111/febs.13365 |
