Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection.

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Bibliographic Details
Title: Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection.
Authors: Pascal KE; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Coleman CM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;, Mujica AO; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Kamat V; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Badithe A; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Fairhurst J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Hunt C; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Strein J; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Berrebi A; Department of Pathology, University of Maryland School of Medicine, Baltimore, MD 21201., Sisk JM; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;, Matthews KL; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;, Babb R; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Chen G; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Lai KM; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Huang TT; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Olson W; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Yancopoulos GD; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591; george@regeneron.com christos.kyratsous@regeneron.com., Stahl N; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591;, Frieman MB; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201;, Kyratsous CA; Regeneron Pharmaceuticals, Inc., Tarrytown, NY 10591; george@regeneron.com christos.kyratsous@regeneron.com.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2015 Jul 14; Vol. 112 (28), pp. 8738-43. Date of Electronic Publication: 2015 Jun 29.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1510830112