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MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.

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Title: MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
Authors: Laberge RM; Buck Institute for Research on Aging, Novato, California 94945, USA., Sun Y; 1] Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Key Lab of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China., Orjalo AV; Buck Institute for Research on Aging, Novato, California 94945, USA., Patil CK; Buck Institute for Research on Aging, Novato, California 94945, USA., Freund A; Buck Institute for Research on Aging, Novato, California 94945, USA., Zhou L; Buck Institute for Research on Aging, Novato, California 94945, USA., Curran SC; Buck Institute for Research on Aging, Novato, California 94945, USA., Davalos AR; Buck Institute for Research on Aging, Novato, California 94945, USA., Wilson-Edell KA; Buck Institute for Research on Aging, Novato, California 94945, USA., Liu S; Buck Institute for Research on Aging, Novato, California 94945, USA., Limbad C; Buck Institute for Research on Aging, Novato, California 94945, USA., Demaria M; Buck Institute for Research on Aging, Novato, California 94945, USA., Li P; Buck Institute for Research on Aging, Novato, California 94945, USA., Hubbard GB; 1] Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [2] Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA., Ikeno Y; 1] Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [2] Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [3] Research Service, San Antonio, Texas 78229, USA [4] GRECC, Audie Murphy VA Hospital (STVHCS), San Antonio, Texas 78229, USA., Javors M; Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA., Desprez PY; 1] Buck Institute for Research on Aging, Novato, California 94945, USA [2] California Pacific Medical Center, Research Institute, San Francisco, California 94107, USA., Benz CC; Buck Institute for Research on Aging, Novato, California 94945, USA., Kapahi P; Buck Institute for Research on Aging, Novato, California 94945, USA., Nelson PS; Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Campisi J; Buck Institute for Research on Aging, Novato, California 94945, USA.
Source: Nature cell biology [Nat Cell Biol] 2015 Aug; Vol. 17 (8), pp. 1049-61. Date of Electronic Publication: 2015 Jul 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation.
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  Data: <searchLink fieldCode="AU" term="%22Laberge+RM%22">Laberge RM</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Sun+Y%22">Sun Y</searchLink>; 1] Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Key Lab of Stem Cell Biology, Institute of Health Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.<br /><searchLink fieldCode="AU" term="%22Orjalo+AV%22">Orjalo AV</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Patil+CK%22">Patil CK</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Freund+A%22">Freund A</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Curran+SC%22">Curran SC</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Davalos+AR%22">Davalos AR</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Wilson-Edell+KA%22">Wilson-Edell KA</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Limbad+C%22">Limbad C</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Demaria+M%22">Demaria M</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Hubbard+GB%22">Hubbard GB</searchLink>; 1] Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [2] Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.<br /><searchLink fieldCode="AU" term="%22Ikeno+Y%22">Ikeno Y</searchLink>; 1] Barshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [2] Department of Pathology, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA [3] Research Service, San Antonio, Texas 78229, USA [4] GRECC, Audie Murphy VA Hospital (STVHCS), San Antonio, Texas 78229, USA.<br /><searchLink fieldCode="AU" term="%22Javors+M%22">Javors M</searchLink>; Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, Texas 78229, USA.<br /><searchLink fieldCode="AU" term="%22Desprez+PY%22">Desprez PY</searchLink>; 1] Buck Institute for Research on Aging, Novato, California 94945, USA [2] California Pacific Medical Center, Research Institute, San Francisco, California 94107, USA.<br /><searchLink fieldCode="AU" term="%22Benz+CC%22">Benz CC</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Kapahi+P%22">Kapahi P</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+PS%22">Nelson PS</searchLink>; Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.<br /><searchLink fieldCode="AU" term="%22Campisi+J%22">Campisi J</searchLink>; Buck Institute for Research on Aging, Novato, California 94945, USA.
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  Data: <searchLink fieldCode="JN" term="%22100890575%22">Nature cell biology</searchLink> [Nat Cell Biol] 2015 Aug; Vol. 17 (8), pp. 1049-61. <i>Date of Electronic Publication: </i>2015 Jul 06.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Macmillan+Magazines+Ltd%22">Macmillan Magazines Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100890575 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4679 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214657392%22">14657392 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cell Biol <i>Subsets: </i>MEDLINE
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