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Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.

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Title: Identification of anti-tumour biologics using primary tumour models, 3-D phenotypic screening and image-based multi-parametric profiling.
Authors: Sandercock AM; MedImmune, Granta Park, Cambridge, CB21 6GH, UK. sandercocka@medimmune.com., Rust S; MedImmune, Granta Park, Cambridge, CB21 6GH, UK. rusts@medimmune.com., Guillard S; MedImmune, Granta Park, Cambridge, CB21 6GH, UK. guillards@medimmune.com., Sachsenmeier KF; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. sachsenmeierk@medimmune.com., Holoweckyj N; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. holoweckyjn@medimmune.com., Hay C; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. hayc@medimmune.com., Flynn M; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. flynnm@medimmune.com., Huang Q; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. huangq@MedImmune.com., Yan K; OcellO, Leiden BioPartner Center, J. H Oortweg 21, 2333 CH, Leiden, The Netherlands. Kuan.yan@OcellO.nl., Herpers B; OcellO, Leiden BioPartner Center, J. H Oortweg 21, 2333 CH, Leiden, The Netherlands. Bram.herpers@OcellO.nl., Price LS; OcellO, Leiden BioPartner Center, J. H Oortweg 21, 2333 CH, Leiden, The Netherlands. Leo.price@OcellO.nl., Soden J; Retrogenix, Crown House, Bingswood Estate, Whaley Bridge, High Peak, SK23 7LY, UK. Jo.Soden@retrogenix.com., Freeth J; Retrogenix, Crown House, Bingswood Estate, Whaley Bridge, High Peak, SK23 7LY, UK. Jim.freeth@retrogenix.com., Jermutus L; MedImmune, Granta Park, Cambridge, CB21 6GH, UK. jermutusl@medimmune.com., Hollingsworth R; MedImmune, One MedImmune Way, Gaithersburg, MD, 20287, USA. hollingsworthr@medimmune.com., Minter R; MedImmune, Granta Park, Cambridge, CB21 6GH, UK. minterr@medimmune.com.
Source: Molecular cancer [Mol Cancer] 2015 Jul 31; Vol. 14, pp. 147. Date of Electronic Publication: 2015 Jul 31.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-4598
DOI:10.1186/s12943-015-0415-0