Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment.

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Title: Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment.
Authors: Modiano JF; Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Masonic Cancer Center, University of Minnesota, 1365 Gortner Avenue, St. Paul, MN, 55108, USA. modiano@umn.edu.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA. modiano@umn.edu.; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA. modiano@umn.edu.; Center for Immunology, University of Minnesota, Minneapolis, MN, USA. modiano@umn.edu., Lindborg BA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.; BRTI Life Sciences, Two Harbors, MN, USA., McElmurry RT; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, MN, USA., Lewellen M; Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Masonic Cancer Center, University of Minnesota, 1365 Gortner Avenue, St. Paul, MN, 55108, USA.; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA., Forster CL; BioNet Histology Research Laboratory, Academic Health Center, University of Minnesota, Minneapolis, MN, USA., Zamora EA; Microbiology, Immunology, and Cancer Biology Graduate Group, University of Minnesota, Minneapolis, MN, USA., Schaack J; Department of Microbiology, School of Medicine, University of Colorado, Aurora, CO, USA.; University of Colorado Cancer Center, Aurora, CO, USA., Bellgrau D; University of Colorado Cancer Center, Aurora, CO, USA.; Integrated Department of Immunology, School of Medicine, University of Colorado, Aurora, CO, USA., O'Brien TD; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.; Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA., Tolar J; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA.; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA.; Department of Pediatrics, School of Medicine, University of Minnesota, Minneapolis, MN, USA.
Source: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2015 Nov; Vol. 64 (11), pp. 1449-60. Date of Electronic Publication: 2015 Aug 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1432-0851
DOI:10.1007/s00262-015-1749-6