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Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.

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Title: Targeting Siglecs with a sialic acid-decorated nanoparticle abrogates inflammation.
Authors: Spence S; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Greene MK; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK., Fay F; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Translational and Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Hams E; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland., Saunders SP; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland., Hamid U; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Fitzgerald M; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Beck J; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Bains BK; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK., Smyth P; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK., Themistou E; School of Chemistry and Chemical Engineering, Queen's University Belfast, Belfast BT9 5AG, UK., Small DM; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Schmid D; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK., O'Kane CM; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Fitzgerald DC; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Abdelghany SM; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. Faculty of Pharmacy, University of Jordan, Amman 11942, Jordan., Johnston JA; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK. Inflammation Research, Amgen Inc., Thousand Oaks, CA 91320, USA., Fallon PG; Trinity Biomedical Sciences Institute, School of Medicine, Trinity College Dublin, Dublin 2, Ireland. National Children's Research Centre, Our Lady's Children's Hospital, Dublin 12, Ireland., Burrows JF; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK., McAuley DF; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Kissenpfennig A; Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Scott CJ; School of Pharmacy, Queen's University Belfast, Belfast BT9 7BL, UK. c.scott@qub.ac.uk.
Source: Science translational medicine [Sci Transl Med] 2015 Sep 02; Vol. 7 (303), pp. 303ra140.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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