The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.
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| Title: | The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity. |
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| Authors: | Mukhopadhyay P; National Institutes of Health, Bethesda, MD, USA., Baggelaar M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Erdelyi K; National Institutes of Health, Bethesda, MD, USA., Cao Z; National Institutes of Health, Bethesda, MD, USA., Cinar R; National Institutes of Health, Bethesda, MD, USA., Fezza F; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy.; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy., Ignatowska-Janlowska B; Virginia Commonwealth University, Richmond, VA, USA., Wilkerson J; Virginia Commonwealth University, Richmond, VA, USA., van Gils N; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands., Hansen T; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Ruben M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Soethoudt M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Heitman L; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands., Kunos G; National Institutes of Health, Bethesda, MD, USA., Maccarrone M; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy.; Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy., Lichtman A; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy., Pacher P; National Institutes of Health, Bethesda, MD, USA., Van der Stelt M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2016 Feb; Vol. 173 (3), pp. 446-58. Date of Electronic Publication: 2016 Jan 15. |
| Publication Type: | Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-5381 |
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| DOI: | 10.1111/bph.13338 |
