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The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.

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Title: The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.
Authors: Mukhopadhyay P; National Institutes of Health, Bethesda, MD, USA., Baggelaar M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Erdelyi K; National Institutes of Health, Bethesda, MD, USA., Cao Z; National Institutes of Health, Bethesda, MD, USA., Cinar R; National Institutes of Health, Bethesda, MD, USA., Fezza F; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy.; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy., Ignatowska-Janlowska B; Virginia Commonwealth University, Richmond, VA, USA., Wilkerson J; Virginia Commonwealth University, Richmond, VA, USA., van Gils N; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands., Hansen T; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Ruben M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Soethoudt M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands., Heitman L; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands., Kunos G; National Institutes of Health, Bethesda, MD, USA., Maccarrone M; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy.; Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy., Lichtman A; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy., Pacher P; National Institutes of Health, Bethesda, MD, USA., Van der Stelt M; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.
Source: British journal of pharmacology [Br J Pharmacol] 2016 Feb; Vol. 173 (3), pp. 446-58. Date of Electronic Publication: 2016 Jan 15.
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity.
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  Data: <searchLink fieldCode="AU" term="%22Mukhopadhyay+P%22">Mukhopadhyay P</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Baggelaar+M%22">Baggelaar M</searchLink>; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Erdelyi+K%22">Erdelyi K</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cao+Z%22">Cao Z</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Cinar+R%22">Cinar R</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Fezza+F%22">Fezza F</searchLink>; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy.; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ignatowska-Janlowska+B%22">Ignatowska-Janlowska B</searchLink>; Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22Wilkerson+J%22">Wilkerson J</searchLink>; Virginia Commonwealth University, Richmond, VA, USA.<br /><searchLink fieldCode="AU" term="%22van+Gils+N%22">van Gils N</searchLink>; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Hansen+T%22">Hansen T</searchLink>; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ruben+M%22">Ruben M</searchLink>; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Soethoudt+M%22">Soethoudt M</searchLink>; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Heitman+L%22">Heitman L</searchLink>; Department of Medicinal Chemistry, Leiden University, Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kunos+G%22">Kunos G</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Maccarrone+M%22">Maccarrone M</searchLink>; European Center for Brain Research/Santa Lucia Foundation, Rome, Italy.; Department of Medicine, Campus Bio-Medico University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Lichtman+A%22">Lichtman A</searchLink>; Department Experimental Medicine & Surgery, Tor Vergata University of Rome, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Pacher+P%22">Pacher P</searchLink>; National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Van+der+Stelt+M%22">Van der Stelt M</searchLink>; Department of Bio-organic Synthesis, Leiden University, Leiden, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%227502536%22">British journal of pharmacology</searchLink> [Br J Pharmacol] 2016 Feb; Vol. 173 (3), pp. 446-58. <i>Date of Electronic Publication: </i>2016 Jan 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7502536 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-5381 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200071188%22">00071188 </searchLink><i>NLM ISO Abbreviation: </i>Br J Pharmacol <i>Subsets: </i>MEDLINE
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