Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke.

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Title: Pre-differentiation of human neural stem cells into GABAergic neurons prior to transplant results in greater repopulation of the damaged brain and accelerates functional recovery after transient ischemic stroke.
Authors: Abeysinghe HC; Neurotrauma Research Team, Department of Medicine, University of Melbourne, Level 4, Clinical Sciences Building, 29 Regent Street, Fitzroy, VIC, 3065, Australia. himaa@student.unimelb.edu.au.; Department of Surgery, University of Melbourne, Melbourne, VIC, Australia. himaa@student.unimelb.edu.au., Bokhari L; Neurotrauma Research Team, Department of Medicine, University of Melbourne, Level 4, Clinical Sciences Building, 29 Regent Street, Fitzroy, VIC, 3065, Australia. laita.bokhari@unimelb.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, VIC, Australia. laita.bokhari@unimelb.edu.au., Quigley A; ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, Innovation Campus, University of Wollongong, Squires Way, Fairy Meadow, NSW 2519, Australia. anita.quigley@svhm.org.au., Choolani M; Department of Obstetrics and Gynecology, National University of Singapore, Singapore, Singapore. mahesh_a_choolani@nuhs.edu.sg., Chan J; Department of Obstetrics and Gynecology, National University of Singapore, Singapore, Singapore. jerrychan@nus.edu.sg., Dusting GJ; Cytoprotection Pharmacology Program, Centre for Eye Research, The Royal Eye and Ear Hospital Melbourne, Melbourne, VIC, Australia. g.dusting@unimelb.edu.au.; Department of Opthamology, Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia. g.dusting@unimelb.edu.au., Crook JM; Department of Surgery, University of Melbourne, Melbourne, VIC, Australia. jcrook@uow.edu.au.; ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, Innovation Campus, University of Wollongong, Squires Way, Fairy Meadow, NSW 2519, Australia. jcrook@uow.edu.au.; Illawarra Health and Medical Research Institute, University of Wollongong, Wollongong, NSW 2522, Australia. jcrook@uow.edu.au., Kobayashi NR; ARC Centre of Excellence for Electromaterials Science, Intelligent Polymer Research Institute, AIIM Facility, Innovation Campus, University of Wollongong, Squires Way, Fairy Meadow, NSW 2519, Australia., Roulston CL; Neurotrauma Research Team, Department of Medicine, University of Melbourne, Level 4, Clinical Sciences Building, 29 Regent Street, Fitzroy, VIC, 3065, Australia. carlir@unimelb.edu.au.; Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Melbourne, VIC, Australia. carlir@unimelb.edu.au.
Source: Stem cell research & therapy [Stem Cell Res Ther] 2015 Sep 29; Vol. 6, pp. 186. Date of Electronic Publication: 2015 Sep 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1757-6512
DOI:10.1186/s13287-015-0175-1