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Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?

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Title: Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?
Authors: Roberts R; ApconiX Ltd, UK. Electronic address: ruth.roberts@apconix.com., Callander R; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK., Duffy P; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK., Jacobsen M; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK., Knight R; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK., Boobis A; Imperial College London, UK.
Source: Regulatory toxicology and pharmacology : RTP [Regul Toxicol Pharmacol] 2015 Dec; Vol. 73 (3), pp. 737-46. Date of Electronic Publication: 2015 Oct 27.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8214983 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0295 (Electronic) Linking ISSN: 02732300 NLM ISO Abbreviation: Regul Toxicol Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?
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  Data: <searchLink fieldCode="AU" term="%22Roberts+R%22">Roberts R</searchLink>; ApconiX Ltd, UK. Electronic address: ruth.roberts@apconix.com.<br /><searchLink fieldCode="AU" term="%22Callander+R%22">Callander R</searchLink>; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK.<br /><searchLink fieldCode="AU" term="%22Duffy+P%22">Duffy P</searchLink>; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK.<br /><searchLink fieldCode="AU" term="%22Jacobsen+M%22">Jacobsen M</searchLink>; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK.<br /><searchLink fieldCode="AU" term="%22Knight+R%22">Knight R</searchLink>; Drug Safety and Metabolism, AstraZeneca, Alderley Park, Macclesfield, UK.<br /><searchLink fieldCode="AU" term="%22Boobis+A%22">Boobis A</searchLink>; Imperial College London, UK.
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  Data: <searchLink fieldCode="JN" term="%228214983%22">Regulatory toxicology and pharmacology : RTP</searchLink> [Regul Toxicol Pharmacol] 2015 Dec; Vol. 73 (3), pp. 737-46. <i>Date of Electronic Publication: </i>2015 Oct 27.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>8214983 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1096-0295 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2202732300%22">02732300 </searchLink><i>NLM ISO Abbreviation: </i>Regul Toxicol Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.yrtph.2015.10.021
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      – Code: eng
        Text: English
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      – TitleFull: Target organ profiles in toxicity studies supporting human dosing: Does severity progress with longer duration of exposure?
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              Text: 2015 Dec
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