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The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.

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Bibliographic Details
Title: The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.
Authors: Qian P; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., He XC; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Paulson A; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Li Z; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA., Tao F; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA., Perry JM; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Guo F; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Zhao M; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Zhi L; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Immuno Microenvironment and Disease of the Educational Ministry, Tianjin Medical University, Tianjin, P.R. China., Venkatraman A; Centre for Stem Cell Research, Christian Medical College, Vellore, 632002, India., Haug JS; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Parmely T; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Li H; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Dobrowsky RT; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS 66045, USA., Ding WX; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA., Kono T; Department of Bioscience, Tokyo University of Agriculture, Tokyo 156-8502, Japan., Ferguson-Smith AC; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK., Li L; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address: lil@stowers.org.
Source: Cell stem cell [Cell Stem Cell] 2016 Feb 04; Vol. 18 (2), pp. 214-28. Date of Electronic Publication: 2015 Nov 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1875-9777
DOI:10.1016/j.stem.2015.11.001