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The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.

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Title: The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.
Authors: Qian P; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., He XC; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Paulson A; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Li Z; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA., Tao F; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA., Perry JM; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Guo F; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Zhao M; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Zhi L; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Immuno Microenvironment and Disease of the Educational Ministry, Tianjin Medical University, Tianjin, P.R. China., Venkatraman A; Centre for Stem Cell Research, Christian Medical College, Vellore, 632002, India., Haug JS; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Parmely T; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Li H; Stowers Institute for Medical Research, Kansas City, MO 64110, USA., Dobrowsky RT; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS 66045, USA., Ding WX; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA., Kono T; Department of Bioscience, Tokyo University of Agriculture, Tokyo 156-8502, Japan., Ferguson-Smith AC; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK., Li L; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address: lil@stowers.org.
Source: Cell stem cell [Cell Stem Cell] 2016 Feb 04; Vol. 18 (2), pp. 214-28. Date of Electronic Publication: 2015 Nov 25.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: The Dlk1-Gtl2 Locus Preserves LT-HSC Function by Inhibiting the PI3K-mTOR Pathway to Restrict Mitochondrial Metabolism.
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  Data: <searchLink fieldCode="AU" term="%22Qian+P%22">Qian P</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22He+XC%22">He XC</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Paulson+A%22">Paulson A</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.<br /><searchLink fieldCode="AU" term="%22Tao+F%22">Tao F</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA.<br /><searchLink fieldCode="AU" term="%22Perry+JM%22">Perry JM</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Guo+F%22">Guo F</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+M%22">Zhao M</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Zhi+L%22">Zhi L</searchLink>; Department of Immunology, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Immuno Microenvironment and Disease of the Educational Ministry, Tianjin Medical University, Tianjin, P.R. China.<br /><searchLink fieldCode="AU" term="%22Venkatraman+A%22">Venkatraman A</searchLink>; Centre for Stem Cell Research, Christian Medical College, Vellore, 632002, India.<br /><searchLink fieldCode="AU" term="%22Haug+JS%22">Haug JS</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Parmely+T%22">Parmely T</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Li+H%22">Li H</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA.<br /><searchLink fieldCode="AU" term="%22Dobrowsky+RT%22">Dobrowsky RT</searchLink>; Department of Pharmacology and Toxicology, University of Kansas, Lawrence, KS 66045, USA.<br /><searchLink fieldCode="AU" term="%22Ding+WX%22">Ding WX</searchLink>; Department of Pharmacology, Toxicology and Therapeutics, University of Kansas Medical Center, Kansas City, KS 66160, USA.<br /><searchLink fieldCode="AU" term="%22Kono+T%22">Kono T</searchLink>; Department of Bioscience, Tokyo University of Agriculture, Tokyo 156-8502, Japan.<br /><searchLink fieldCode="AU" term="%22Ferguson-Smith+AC%22">Ferguson-Smith AC</searchLink>; Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EG, UK.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Stowers Institute for Medical Research, Kansas City, MO 64110, USA; Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, KS 66160, USA. Electronic address: lil@stowers.org.
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  Data: <searchLink fieldCode="JN" term="%22101311472%22">Cell stem cell</searchLink> [Cell Stem Cell] 2016 Feb 04; Vol. 18 (2), pp. 214-28. <i>Date of Electronic Publication: </i>2015 Nov 25.
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