Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety.

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Title: Gene Delivery by Subconjunctival Injection of Adenovirus in Rats: A Study of Local Distribution, Transgene Duration and Safety.
Authors: Liu GS; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Victoria, Australia., Wang JH; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Victoria, Australia., Lee JH; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia., Tsai PJ; Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Tsai HE; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan., Sheu SJ; Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Lin HC; Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan., Dusting GJ; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia.; Ophthalmology, Department of Surgery, University of Melbourne, East Melbourne, Victoria, Australia., Tai MH; Institute of Biomedical Sciences, National Sun Yat-Sen University, Kaohsiung, Taiwan., Bee YS; Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.; National Defense Medical Center, Taipei, Taiwan.; Yuh-Ing Junior College of Health Care & Management, Kaohsiung, Taiwan.
Source: PloS one [PLoS One] 2015 Dec 07; Vol. 10 (12), pp. e0143956. Date of Electronic Publication: 2015 Dec 07 (Print Publication: 2015).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1932-6203
DOI:10.1371/journal.pone.0143956