Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.

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Title: Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
Authors: Williams JR; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Trias E; Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; Institut Pasteur de Montevideo, Uruguay., Beilby PR; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Lopez NI; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Labut EM; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Bradford CS; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Roberts BR; Florey Institute, University of Melbourne, Australia., McAllum EJ; Florey Institute, University of Melbourne, Australia; Department of Pathology, University of Melbourne, Australia., Crouch PJ; Florey Institute, University of Melbourne, Australia; Department of Pathology, University of Melbourne, Australia., Rhoads TW; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States., Pereira C; Department of Statistics, Oregon State University, United States., Son M; Department of Neurology, University of Texas Southwestern, Dallas, Texas, United States., Elliott JL; Department of Neurology, University of Texas Southwestern, Dallas, Texas, United States., Franco MC; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States., Estévez AG; Burnett School of Biomedical Sciences, College of Medicine, University of Central Florida, Orlando, Florida, United States., Barbeito L; Institut Pasteur de Montevideo, Uruguay., Beckman JS; Linus Pauling Institute, Department of Biochemistry and Biophysics, Oregon State University, United States. Electronic address: joe.beckman@oregonstate.edu.
Source: Neurobiology of disease [Neurobiol Dis] 2016 May; Vol. 89, pp. 1-9. Date of Electronic Publication: 2016 Jan 27.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1095-953X
DOI:10.1016/j.nbd.2016.01.020