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Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.

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Bibliographic Details
Title: Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.
Authors: Hoop CL; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Lin HK; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Kar K; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Magyarfalvi G; Laboratory of Molecular Spectroscopy, Institute of Chemistry, Eötvös University, H-1518, Budapest 112, Hungary;, Lamley JM; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom., Boatz JC; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Mandal A; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Lewandowski JR; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom., Wetzel R; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, van der Wel PC; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; vanderwel@pitt.edu.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Feb 09; Vol. 113 (6), pp. 1546-51. Date of Electronic Publication: 2016 Feb 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.1521933113