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Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.

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Title: Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.
Authors: Hoop CL; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Lin HK; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Kar K; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Magyarfalvi G; Laboratory of Molecular Spectroscopy, Institute of Chemistry, Eötvös University, H-1518, Budapest 112, Hungary;, Lamley JM; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom., Boatz JC; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Mandal A; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, Lewandowski JR; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom., Wetzel R; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;, van der Wel PC; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; vanderwel@pitt.edu.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2016 Feb 09; Vol. 113 (6), pp. 1546-51. Date of Electronic Publication: 2016 Feb 01.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Huntingtin exon 1 fibrils feature an interdigitated β-hairpin-based polyglutamine core.
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  Data: <searchLink fieldCode="AU" term="%22Hoop+CL%22">Hoop CL</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22Lin+HK%22">Lin HK</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22Kar+K%22">Kar K</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22Magyarfalvi+G%22">Magyarfalvi G</searchLink>; Laboratory of Molecular Spectroscopy, Institute of Chemistry, Eötvös University, H-1518, Budapest 112, Hungary;<br /><searchLink fieldCode="AU" term="%22Lamley+JM%22">Lamley JM</searchLink>; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Boatz+JC%22">Boatz JC</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22Mandal+A%22">Mandal A</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22Lewandowski+JR%22">Lewandowski JR</searchLink>; Department of Chemistry, University of Warwick, Coventry CV4 7AL, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Wetzel+R%22">Wetzel R</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260;<br /><searchLink fieldCode="AU" term="%22van+der+Wel+PC%22">van der Wel PC</searchLink>; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260; vanderwel@pitt.edu.
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  Data: <searchLink fieldCode="JN" term="%227505876%22">Proceedings of the National Academy of Sciences of the United States of America</searchLink> [Proc Natl Acad Sci U S A] 2016 Feb 09; Vol. 113 (6), pp. 1546-51. <i>Date of Electronic Publication: </i>2016 Feb 01.
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              Text: 2016 Feb 09
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