4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling.
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| Title: | 4,6-Diphenylpyridines as Promising Novel Anti-Influenza Agents Targeting the PA-PB1 Protein-Protein Interaction: Structure-Activity Relationships Exploration with the Aid of Molecular Modeling. |
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| Authors: | Trist IM; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Nannetti G; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Tintori C; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Fallacara AL; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Deodato D; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy., Mercorelli B; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Palù G; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Wijtmans M; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Gospodova T; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria., Edink E; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Verheij M; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., de Esch I; Division of Medicinal Chemistry, Amsterdam Institute for Molecules, Medicines and Systems, VU University Amsterdam , De Boelelaan 1083, 1081 HV Amsterdam, The Netherlands., Viteva L; Institute of Organic Chemistry with Centre of Phytochemistry, Bulgarian Academy of Sciences , Acad. Georgy Bonchev str. BI. 9, 1113 Sofia, Bulgaria., Loregian A; Dipartimento di Medicina Molecolare, Università degli Studi di Padova , Via A. Gabelli 63, I-35121 Padova, Italy., Botta M; Dipartimento di Biotecnologie, Chimica e Farmacia, Università degli Studi di Siena , Via A. Moro, I-53100 Siena, Italy.; Sbarro Institute for Cancer Research and Molecular Medicine, Temple University , BioLife Science Building, Suite 333, 1900 N 12th Street, Philadelphia, Pennsylvania 19122, United States. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2016 Mar 24; Vol. 59 (6), pp. 2688-703. Date of Electronic Publication: 2016 Mar 11. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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