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Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol.

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Title: Multicentre open-label randomised controlled trial to compare colistin alone with colistin plus meropenem for the treatment of severe infections caused by carbapenem-resistant Gram-negative infections (AIDA): a study protocol.
Authors: Dickstein Y; Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Leibovici L; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Yahav D; Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel Unit of Infectious Diseases, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel., Eliakim-Raz N; Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel Unit of Infectious Diseases, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel., Daikos GL; First Department of Medicine, University of Athens, Athens, Greece., Skiada A; First Department of Medicine, University of Athens, Athens, Greece., Antoniadou A; Fourth Department of Medicine, University of Athens, Athens, Greece., Carmeli Y; Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Nutman A; Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Levi I; Division of Epidemiology and Preventive Medicine, Tel Aviv Sourasky Medical Centre, Tel Aviv, Israel., Adler A; Microbiology Laboratory, Tel Aviv Sourasky Medical Centre, Tel-Aviv, Israel., Durante-Mangoni E; Internal Medicine, Second University of Naples, Monaldi Hospital-AORN dei Colli, Napoli, Italy., Andini R; Internal Medicine, Second University of Naples, Monaldi Hospital-AORN dei Colli, Napoli, Italy., Cavezza G; Internal Medicine, Second University of Naples, Monaldi Hospital-AORN dei Colli, Napoli, Italy., Mouton JW; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands Department of Medical Microbiology, Radboudumc, Nijmegen, The Netherlands., Wijma RA; Department of Medical Microbiology and Infectious Diseases, Erasmus MC, Rotterdam, The Netherlands., Theuretzbacher U; Center for Anti-Infective Agents, Vienna, Austria., Friberg LE; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Kristoffersson AN; Department of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden., Zusman O; Department of Medicine E, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel Sackler Faculty of Medicine, Tel-Aviv University, Ramat-Aviv, Israel., Koppel F; Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Dishon Benattar Y; Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel., Altunin S; Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel., Paul M; Division of Infectious Diseases, Rambam Health Care Campus, Haifa, Israel Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel.
Corporate Authors: AIDA consortium
Source: BMJ open [BMJ Open] 2016 Apr 20; Vol. 6 (4), pp. e009956. Date of Electronic Publication: 2016 Apr 20.
Publication Type: Clinical Trial, Phase IV; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2015-009956