The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor-Mediated Cross-Linking.

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Title: The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor-Mediated Cross-Linking.
Authors: Overdijk MB; Genmab, 3584 CM Utrecht, the Netherlands;, Jansen JH; Immunotherapy Laboratory, Laboratory for Translational Immunology, University Medical Center, 3584 CX Utrecht, the Netherlands;, Nederend M; Immunotherapy Laboratory, Laboratory for Translational Immunology, University Medical Center, 3584 CX Utrecht, the Netherlands;, Lammerts van Bueren JJ; Genmab, 3584 CM Utrecht, the Netherlands;, Groen RW; Department of Cell Biology, University Medical Center, 3584 CX Utrecht, the Netherlands;, Parren PW; Genmab, 3584 CM Utrecht, the Netherlands; Department of Cancer and Inflammation Research, Institute of Molecular Medicine, University of Southern Denmark, 5000 Odense, Denmark; and Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2300 RC Leiden, the Netherlands., Leusen JH; Immunotherapy Laboratory, Laboratory for Translational Immunology, University Medical Center, 3584 CX Utrecht, the Netherlands; jleusen@umcutrecht.nl., Boross P; Immunotherapy Laboratory, Laboratory for Translational Immunology, University Medical Center, 3584 CX Utrecht, the Netherlands;
Source: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2016 Aug 01; Vol. 197 (3), pp. 807-13. Date of Electronic Publication: 2016 Jun 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1550-6606
DOI:10.4049/jimmunol.1501351