Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

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Title: Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
Authors: Thienpont B; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., Steinbacher J; Department für Chemie und Pharmazie, Ludwig-Maximilians-Universität, München, Germany., Zhao H; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., D'Anna F; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., Kuchnio A; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium., Ploumakis A; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Ghesquière B; Vesalius Research Center, VIB, Leuven, Belgium., Van Dyck L; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., Boeckx B; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium., Schoonjans L; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium., Hermans E; Gynecologic Oncology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium., Amant F; Gynecologic Oncology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium., Kristensen VN; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway., Peng Koh K; Department of Development and Regeneration, and Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium., Mazzone M; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Molecular Oncology and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium., Coleman M; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK., Carell T; Department für Chemie und Pharmazie, Ludwig-Maximilians-Universität, München, Germany., Carmeliet P; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium., Lambrechts D; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.
Source: Nature [Nature] 2016 Sep 01; Vol. 537 (7618), pp. 63-68. Date of Electronic Publication: 2016 Aug 17.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Tumour hypoxia causes DNA hypermethylation by reducing TET activity.
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  Data: <searchLink fieldCode="AU" term="%22Thienpont+B%22">Thienpont B</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Steinbacher+J%22">Steinbacher J</searchLink>; Department für Chemie und Pharmazie, Ludwig-Maximilians-Universität, München, Germany.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22D'Anna+F%22">D'Anna F</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kuchnio+A%22">Kuchnio A</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Ploumakis+A%22">Ploumakis A</searchLink>; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Ghesquière+B%22">Ghesquière B</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Van+Dyck+L%22">Van Dyck L</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Boeckx+B%22">Boeckx B</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Schoonjans+L%22">Schoonjans L</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Hermans+E%22">Hermans E</searchLink>; Gynecologic Oncology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Amant+F%22">Amant F</searchLink>; Gynecologic Oncology, University Hospitals Leuven, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Kristensen+VN%22">Kristensen VN</searchLink>; Department of Genetics, Institute for Cancer Research, Oslo University Hospital Radiumhospitalet, Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Peng+Koh+K%22">Peng Koh K</searchLink>; Department of Development and Regeneration, and Stem Cell Institute Leuven, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Mazzone+M%22">Mazzone M</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Molecular Oncology and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Coleman+M%22">Coleman M</searchLink>; Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Carell+T%22">Carell T</searchLink>; Department für Chemie und Pharmazie, Ludwig-Maximilians-Universität, München, Germany.<br /><searchLink fieldCode="AU" term="%22Carmeliet+P%22">Carmeliet P</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Lambrechts+D%22">Lambrechts D</searchLink>; Vesalius Research Center, VIB, Leuven, Belgium.; Laboratory of Translational Genetics, Department of Oncology, KU Leuven, Leuven, Belgium.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2016 Sep 01; Vol. 537 (7618), pp. 63-68. <i>Date of Electronic Publication: </i>2016 Aug 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE
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