MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering.

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Title: MAR-Mediated transgene integration into permissive chromatin and increased expression by recombination pathway engineering.
Authors: Kostyrko K; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland., Neuenschwander S; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Junier T; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Regamey A; Selexis SA, Geneva, Switzerland., Iseli C; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Schmid-Siegert E; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bosshard S; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland., Majocchi S; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland., Le Fourn V; Selexis SA, Geneva, Switzerland., Girod PA; Selexis SA, Geneva, Switzerland., Xenarios I; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Mermod N; Department of Fundamental Microbiology, Institute of Biotechnology, University of Lausanne, and Center for Biotechnology UNIL-EPFL, Lausanne, Switzerland.
Source: Biotechnology and bioengineering [Biotechnol Bioeng] 2017 Feb; Vol. 114 (2), pp. 384-396. Date of Electronic Publication: 2016 Oct 03.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1097-0290
DOI:10.1002/bit.26086