Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.

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Title: Metabolomic signatures of drug response phenotypes for ketamine and esketamine in subjects with refractory major depressive disorder: new mechanistic insights for rapid acting antidepressants.
Authors: Rotroff DM; Department of Statistics, North Carolina State University, Raleigh, NC, USA.; Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA., Corum DG; Department of Drug Discovery and Biomedical Sciences, Medical University of South Carolina, Charleston, SC, USA., Motsinger-Reif A; Department of Statistics, North Carolina State University, Raleigh, NC, USA.; Bioinformatics Research Center, North Carolina State University, Raleigh, NC, USA., Fiehn O; UC Davis Genome Center, University of California Davis, Davis, CA, USA.; Department of Biochemistry, King Abdulaziz University, Jeddah, Saudi Arabia., Bottrel N; Department of Neuroscience, Janssen Research and Development, Titusville, NJ, USA., Drevets WC; Department of Neuroscience, Janssen Research and Development, Titusville, NJ, USA., Singh J; Department of Neuroscience, Janssen Research and Development, San Diego CA, USA., Salvadore G; Department of Neuroscience, Janssen Research and Development, Titusville, NJ, USA., Kaddurah-Daouk R; Department of Psychiatry, Duke University Medical Center, Durham NC, USA.; Duke Institute for Brain Sciences, Duke University, Durham, NC, USA.
Source: Translational psychiatry [Transl Psychiatry] 2016 Sep 20; Vol. 6 (9), pp. e894. Date of Electronic Publication: 2016 Sep 20.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2158-3188
DOI:10.1038/tp.2016.145