Effects of the Janus Kinase Inhibitor, Tofacitinib, on Testicular Leydig Cell Hyperplasia and Adenoma in Rats, and on Prolactin Signaling in Cultured Primary Rat Leydig Cells.

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Title: Effects of the Janus Kinase Inhibitor, Tofacitinib, on Testicular Leydig Cell Hyperplasia and Adenoma in Rats, and on Prolactin Signaling in Cultured Primary Rat Leydig Cells.
Authors: Chapin RE; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340 robert.e.chapin@pfizer.com.; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340., Ball DJ; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340., Radi ZA; Pfizer Drug Safety R&D, 1 Burtt Rd, Andover, Massachusetts 08010., Kumpf SW; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340., Koza-Taylor PH; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340., Potter DM; Pfizer Drug Safety R&D, Eastern Point Rd, Groton, Connecticut 06340., Mark Vogel W; Pfizer Drug Safety R&D, 610 Main St, Cambridge, Massachusetts 02139.
Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2017 Jan; Vol. 155 (1), pp. 148-156. Date of Electronic Publication: 2016 Oct 05.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0929
DOI:10.1093/toxsci/kfw197