Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients.

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Title: Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients.
Authors: Rivas JR; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Ireland SJ; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Chkheidze R; Department of Pathology, UT Southwestern, Dallas, TX, USA., Rounds WH; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Lim J; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Johnson J; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Ramirez DM; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Ligocki AJ; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Chen D; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Guzman AA; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Woodhall M; Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Wilson PC; Department of Biomedical Sciences, University of Chicago, Chicago, IL, USA., Meffre E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA., White C 3rd; Department of Pathology, UT Southwestern, Dallas, TX, USA., Greenberg BM; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Waters P; Department of Clinical Neurosciences, University of Oxford, Oxford, UK., Cowell LG; Department of Clinical Science, UT Southwestern, Dallas, TX, USA., Stowe AM; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA., Monson NL; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA. Nancy.Monson@UTSouthwestern.edu.; Department of Immunology, UT Southwestern, Dallas, TX, USA. Nancy.Monson@UTSouthwestern.edu.
Source: Acta neuropathologica [Acta Neuropathol] 2017 Jan; Vol. 133 (1), pp. 43-60. Date of Electronic Publication: 2016 Oct 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Peripheral VH4+ plasmablasts demonstrate autoreactive B cell expansion toward brain antigens in early multiple sclerosis patients.
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  Data: <searchLink fieldCode="AU" term="%22Rivas+JR%22">Rivas JR</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ireland+SJ%22">Ireland SJ</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chkheidze+R%22">Chkheidze R</searchLink>; Department of Pathology, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rounds+WH%22">Rounds WH</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Lim+J%22">Lim J</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Johnson+J%22">Johnson J</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez+DM%22">Ramirez DM</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ligocki+AJ%22">Ligocki AJ</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Chen+D%22">Chen D</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Guzman+AA%22">Guzman AA</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Woodhall+M%22">Woodhall M</searchLink>; Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Wilson+PC%22">Wilson PC</searchLink>; Department of Biomedical Sciences, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Meffre+E%22">Meffre E</searchLink>; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22White+C+3rd%22">White C 3rd</searchLink>; Department of Pathology, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Greenberg+BM%22">Greenberg BM</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Waters+P%22">Waters P</searchLink>; Department of Clinical Neurosciences, University of Oxford, Oxford, UK.<br /><searchLink fieldCode="AU" term="%22Cowell+LG%22">Cowell LG</searchLink>; Department of Clinical Science, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Stowe+AM%22">Stowe AM</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Monson+NL%22">Monson NL</searchLink>; Department of Neurology and Neurotherapeutics, UT Southwestern, Dallas, TX, USA. Nancy.Monson@UTSouthwestern.edu.; Department of Immunology, UT Southwestern, Dallas, TX, USA. Nancy.Monson@UTSouthwestern.edu.
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  Data: <searchLink fieldCode="JN" term="%220412041%22">Acta neuropathologica</searchLink> [Acta Neuropathol] 2017 Jan; Vol. 133 (1), pp. 43-60. <i>Date of Electronic Publication: </i>2016 Oct 11.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer+Verlag%22">Springer Verlag </searchLink><i>Country of Publication: </i>Germany <i>NLM ID: </i>0412041 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1432-0533 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200016322%22">00016322 </searchLink><i>NLM ISO Abbreviation: </i>Acta Neuropathol <i>Subsets: </i>MEDLINE
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