Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.

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Title: Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia.
Authors: Gu Z; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Churchman M; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Roberts K; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Li Y; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Liu Y; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Harvey RC; University of New Mexico Cancer Center, Albuquerque, New Mexico 87106, USA., McCastlain K; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Reshmi SC; The Research Institute, Nationwide Children's Hospital, Columbus, Ohio 43205, USA., Payne-Turner D; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Iacobucci I; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA., Shao Y; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA.; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Chen IM; University of New Mexico Cancer Center, Albuquerque, New Mexico 87106, USA., Valentine M; Cytogenetic Shared Resource, St Jude Children's Research Hospital, Memphis, Tennessee 38105, USA., Pei D; Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee 38105., Mungall KL; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Mungall AJ; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Ma Y; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Moore R; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Marra M; Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC V5Z 4S6, Canada., Stonerock E; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio 43205, USA.; Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA., Gastier-Foster JM; Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio 43205, USA.; Department of Pathology, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA.; Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio 43210, USA., Devidas M; Department of Biostatistics, Colleges of Medicine and Public Health &Health Professions, University of Florida, Gainesville, Florida 32611, USA., Dai Y; Department of Biostatistics, Colleges of Medicine and Public Health &Health Professions, University of Florida, Gainesville, Florida 32611, USA., Wood B; Department of Laboratory Medicine, University of Washington, Seattle, Washington 98195, USA., Borowitz M; Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA., Larsen EE; Maine Children's Cancer Program, Scarborough, Maine 04074, USA., Maloney K; Pediatric Hematology/Oncology/BMT, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, Colorado 80045, USA., Mattano LA Jr; HARP Pharma Consulting, Mystic, Connecticut 06355, USA., Angiolillo A; Children's National Medical Center, Washington, DC 20010, USA., Salzer WL; US Army Medical Research and Materiel Command, Fort Detrick, Maryland 21702, USA., Burke MJ; Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA., Gianni F; Department of Hematology and Bone Marrow Transplantation, Papa Giovanni XXIII Hospital Piazza OMS 1 24127, Bergamo, Italy., Spinelli O; Department of Hematology and Bone Marrow Transplantation, Papa Giovanni XXIII Hospital Piazza OMS 1 24127, Bergamo, Italy., Radich JP; Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Minden MD; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 2M9, Canada., Moorman AV; Leukemia Research Cytogenetics Group, Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE1 7RU, UK., Patel B; Department of Haemato-Oncology, Barts Cancer Institute, London EC1M 6BQ, UK., Fielding AK; Department of Hematology, UCL Cancer Institute, London WC1E 6BT, UK., Rowe JM; Hematology, Shaare Zedek Medical Center, Jerusalem 9103102, Israel., Luger SM; Abramson Cancer Center, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Bhatia R; Division of Hematology and Oncology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Aldoss I; Division of Hematology and Oncology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Forman SJ; Gehr Family Center for Leukemia Research, City of Hope, Duarte, California 91010, USA., Kohlschmidt J; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA.; Alliance for Clinical Trials in Oncology Statistics and Data Center, Mayo Clinic, Rochester, Minnesota 55905, USA., Mrózek K; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., Marcucci G; Gehr Family Center for Leukemia Research, City of Hope, Duarte, California 91010, USA., Bloomfield CD; The Ohio State University Comprehensive Cancer Center, Columbus, Ohio 43210, USA., Stock W; University of Chicago Medical Center, Chicago, Illinois 60637, USA., Kornblau S; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Kantarjian HM; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Konopleva M; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA., Paietta E; Cancer Center, Montefiore Medical Center North Division, Bronx, New York 10467, USA., Willman CL; University of New Mexico Cancer Center, Albuquerque, New Mexico 87106, USA., Loh ML; Department of Pediatrics, Benioff Children's Hospital, San Francisco, California 94158, USA.; Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94115, USA., Hunger SP; Children's Hospital of Philadelphia, Philadelphia, Pennsylvania 19104, USA.; Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA., Mullighan CG; Department of Pathology and Hematological Malignancies Program, St Jude Children's Research Hospital, 262 Danny Thomas Place, MS 342, Memphis, Tennessee 38105, USA.
Source: Nature communications [Nat Commun] 2016 Nov 08; Vol. 7, pp. 13331. Date of Electronic Publication: 2016 Nov 08.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2041-1723
DOI:10.1038/ncomms13331