Development of a high-throughput crystal structure-determination platform for JAK1 using a novel metal-chelator soaking system.
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| Title: | Development of a high-throughput crystal structure-determination platform for JAK1 using a novel metal-chelator soaking system. |
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| Authors: | Caspers NL; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Han S; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Rajamohan F; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Hoth LR; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Geoghegan KF; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Subashi TA; Pharmacokinetics, Dynamics and Metabolism, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA., Vazquez ML; Inflammation Medicinal Chemistry, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Kaila N; Inflammation Medicinal Chemistry, Pfizer Inc., 610 Main Street, Cambridge, MA 02139, USA., Cronin CN; Oncology Structural Biology, Pfizer Inc., 10770 Science Center Drive, San Diego, CA 92121, USA., Johnson E; Oncology Structural Biology, Pfizer Inc., 10770 Science Center Drive, San Diego, CA 92121, USA., Kurumbail RG; Structural Biology, Pfizer Inc., Eastern Point Road, Groton, CT 06340, USA. |
| Source: | Acta crystallographica. Section F, Structural biology communications [Acta Crystallogr F Struct Biol Commun] 2016 Nov 01; Vol. 72 (Pt 11), pp. 840-845. Date of Electronic Publication: 2016 Oct 27. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: John Wiley & Sons Inc Country of Publication: United States NLM ID: 101620319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2053-230X (Electronic) Linking ISSN: 2053230X NLM ISO Abbreviation: Acta Crystallogr F Struct Biol Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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