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Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population.

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Title: Functional Investigations of HNF1A Identify Rare Variants as Risk Factors for Type 2 Diabetes in the General Population.
Authors: Najmi LA; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Biomedicine, University of Bergen, Bergen, Norway., Aukrust I; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Flannick J; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA., Molnes J; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway., Burtt N; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA., Molven A; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway., Groop L; Department of Clinical Sciences, Diabetes and Endocrinology, Clinical Research Center, Lund University, Malmö, Sweden., Altshuler D; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA.; Departments of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, MA., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Bjørkhaug L; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Biomedical Laboratory Sciences, Bergen University College, Bergen, Norway., Njølstad PR; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway pal.njolstad@uib.no lise.b.gundersen@hvl.no.; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
Source: Diabetes [Diabetes] 2017 Feb; Vol. 66 (2), pp. 335-346. Date of Electronic Publication: 2016 Nov 29.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Diabetes Association Country of Publication: United States NLM ID: 0372763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-327X (Electronic) Linking ISSN: 00121797 NLM ISO Abbreviation: Diabetes Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Najmi+LA%22">Najmi LA</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.; Department of Biomedicine, University of Bergen, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Aukrust+I%22">Aukrust I</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Flannick+J%22">Flannick J</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Molnes+J%22">Molnes J</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Burtt+N%22">Burtt N</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Molven+A%22">Molven A</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Bergen, Norway.; Department of Pathology, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Groop+L%22">Groop L</searchLink>; Department of Clinical Sciences, Diabetes and Endocrinology, Clinical Research Center, Lund University, Malmö, Sweden.<br /><searchLink fieldCode="AU" term="%22Altshuler+D%22">Altshuler D</searchLink>; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, MA.; Departments of Genetics and Medicine, Harvard Medical School, Boston, MA.; Departments of Molecular Biology and Diabetes Unit, Massachusetts General Hospital, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Johansson+S%22">Johansson S</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Bjørkhaug+L%22">Bjørkhaug L</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Department of Biomedical Laboratory Sciences, Bergen University College, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Njølstad+PR%22">Njølstad PR</searchLink>; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway pal.njolstad@uib.no lise.b.gundersen@hvl.no.; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Diabetes+Association%22">American Diabetes Association </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0372763 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1939-327X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200121797%22">00121797 </searchLink><i>NLM ISO Abbreviation: </i>Diabetes <i>Subsets: </i>MEDLINE
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