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Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation.

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Bibliographic Details
Title: Backbone Engineering within a Latent β-Hairpin Structure to Design Inhibitors of Polyglutamine Amyloid Formation.
Authors: Kar K; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA., Baker MA; Department of Chemistry, Kenneth P. Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA., Lengyel GA; Department of Chemistry, Kenneth P. Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA., Hoop CL; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA., Kodali R; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA., Byeon IJ; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA., Horne WS; Department of Chemistry, Kenneth P. Dietrich School of Arts and Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA., van der Wel PC; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA., Wetzel R; Department of Structural Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, USA. Electronic address: rwetzel@pitt.edu.
Source: Journal of molecular biology [J Mol Biol] 2017 Jan 20; Vol. 429 (2), pp. 308-323. Date of Electronic Publication: 2016 Dec 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1089-8638
DOI:10.1016/j.jmb.2016.12.010