HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation.
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| Title: | HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation. |
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| Authors: | Myant KB; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk.; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Cammareri P; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK., Hodder MC; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK., Wills J; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Von Kriegsheim A; Cancer Research UK Edinburgh Centre, The Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK., Győrffy B; MTA TTK Lendület Cancer Biomarker Research Group, Budapest, Hungary.; 2nd Department of Pediatrics, Semmelweis University, Budapest, Hungary., Rashid M; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Polo S; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy., Maspero E; IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy., Vaughan L; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK., Gurung B; Boston Children's Hospital, Boston, MA, USA., Barry E; Boston Children's Hospital, Boston, MA, USA., Malliri A; Cancer Research UK Manchester Institute, The University of Manchester, Withington, Manchester, UK., Camargo F; Boston Children's Hospital, Boston, MA, USA., Adams DJ; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Iavarone A; Departments of Neurology and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA., Lasorella A; Departments of Pediatrics and Pathology, Institute for Cancer Genetics, Irving Comprehensive Research Center, New York, NY, USA., Sansom OJ; Cancer Research UK Beatson Institute, Garscube Estate, Bearsden, Glasgow, UK kevin.myant@igmm.ed.ac.uk o.sansom@beatson.gla.ac.uk. |
| Source: | EMBO molecular medicine [EMBO Mol Med] 2017 Feb; Vol. 9 (2), pp. 181-197. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1757-4684 |
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| DOI: | 10.15252/emmm.201606684 |
