One amino acid in mouse activated factor VII defines its endothelial protein C receptor (EPCR) binding and modulates its EPCR-dependent hemostatic activity in vivo.

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Title: One amino acid in mouse activated factor VII defines its endothelial protein C receptor (EPCR) binding and modulates its EPCR-dependent hemostatic activity in vivo.
Authors: Pavani G; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Zintner SM; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Ivanciu L; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA., Small JC; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Stafford KA; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Szeto JH; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA., Margaritis P; Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; The Raymond G. Perelman Center for Cellular and Molecular Therapeutics, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.; The University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Source: Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2017 Mar; Vol. 15 (3), pp. 507-512. Date of Electronic Publication: 2017 Feb 14.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 101170508 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-7836 (Electronic) Linking ISSN: 15387836 NLM ISO Abbreviation: J Thromb Haemost Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-7836
DOI:10.1111/jth.13607