Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.

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Title: Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.
Authors: Peirs S; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Frismantas V; Department of Pediatric Oncology, Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Matthijssens F; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Van Loocke W; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Pieters T; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Molecular and Cellular Oncology Lab, VIB Inflammation Research Center, Ghent University, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Vandamme N; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Molecular and Cellular Oncology Lab, VIB Inflammation Research Center, Ghent University, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Lintermans B; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Dobay MP; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland., Berx G; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Molecular and Cellular Oncology Lab, VIB Inflammation Research Center, Ghent University, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Poppe B; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium., Goossens S; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.; Molecular and Cellular Oncology Lab, VIB Inflammation Research Center, Ghent University, Ghent, Belgium.; Department of Biomedical Molecular Biology, Ghent University, Ghent, Belgium., Bornhauser BC; Department of Pediatric Oncology, Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Bourquin JP; Department of Pediatric Oncology, Children's Research Centre, University Children's Hospital Zurich, Zurich, Switzerland., Van Vlierberghe P; Center for Medical Genetics, Ghent University, Ghent, Belgium.; Cancer Research Institute Ghent (CRIG), Ghent, Belgium.
Source: Leukemia [Leukemia] 2017 Oct; Vol. 31 (10), pp. 2037-2047. Date of Electronic Publication: 2017 Jan 11.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5551
DOI:10.1038/leu.2017.10