Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function.
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| Title: | Targeting Aurora kinase A and JAK2 prevents GVHD while maintaining Treg and antitumor CTL function. |
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| Authors: | Betts BC; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA. brian.betts@moffitt.org.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Veerapathran A; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA., Pidala J; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Yang H; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Horna P; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Hematopathology and Laboratory Medicine, Moffitt Cancer Center, Tampa, FL 33612, USA., Walton K; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA., Cubitt CL; Translational Research Core, Moffitt Cancer Center, Tampa, FL 33612, USA., Gunawan S; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA., Lawrence HR; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Lawrence NJ; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Sebti SM; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA.; Department of Drug Discovery, Moffitt Cancer Center, Tampa, FL 33612, USA., Anasetti C; Department of Blood and Marrow Transplantation, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Immunology, Moffitt Cancer Center, Tampa, FL 33612, USA.; Department of Oncologic Sciences, University of South Florida, Tampa, FL 33612, USA. |
| Source: | Science translational medicine [Sci Transl Med] 2017 Jan 11; Vol. 9 (372). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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