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Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies.

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Title: Meta-GWAS Accuracy and Power (MetaGAP) Calculator Shows that Hiding Heritability Is Partially Due to Imperfect Genetic Correlations across Studies.
Authors: de Vlaming R; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands., Okbay A; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands., Rietveld CA; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands., Johannesson M; Department of Economics, Stockholm School of Economics, Stockholm, Sweden., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Uitterlinden AG; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., van Rooij FJ; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Hofman A; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, United States of America., Groenen PJ; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Econometric Institute, Erasmus School of Economics, Rotterdam, the Netherlands., Thurik AR; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Montpellier Business School, Montpellier, France., Koellinger PD; Erasmus University Rotterdam Institute for Behavior and Biology, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Applied Economics, Erasmus School of Economics, Rotterdam, the Netherlands.; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam, the Netherlands.
Source: PLoS genetics [PLoS Genet] 2017 Jan 17; Vol. 13 (1), pp. e1006495. Date of Electronic Publication: 2017 Jan 17 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1553-7404
DOI:10.1371/journal.pgen.1006495