Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion.

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Title:	Scalable Design of Paired CRISPR Guide RNAs for Genomic Deletion.
Authors:	Pulido-Quetglas C; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Aparicio-Prat E; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Arnan C; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Polidori T; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Hermoso T; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Palumbo E; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Ponomarenko J; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Guigo R; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain., Johnson R; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Dr. Aiguader 88, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain.; Department of Clinical Research, University of Bern, Bern, Switzerland.; Department of Medical Oncology, Inselspital, University Hospital and University of Bern, Bern, Switzerland.
Source:	PLoS computational biology [PLoS Comput Biol] 2017 Mar 02; Vol. 13 (3), pp. e1005341. Date of Electronic Publication: 2017 Mar 02 (Print Publication: 2017).
Publication Type:	Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info:	Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1553-7358
DOI:	10.1371/journal.pcbi.1005341