Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.

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Title: Microglial complement receptor 3 regulates brain Aβ levels through secreted proteolytic activity.
Authors: Czirr E; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Castello NA; Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158., Mosher KI; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Castellano JM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305., Hinkson IV; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305.; Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304., Lucin KM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Baeza-Raja B; Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158., Ryu JK; Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158., Li L; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305.; Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304., Farina SN; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305.; Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304., Belichenko NP; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Longo FM; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Akassoglou K; Gladstone Institute of Neurological Disease, University of California, San Francisco, San Francisco, CA 94158.; Department of Neurology, University of California, San Francisco, San Francisco, CA 94158., Britschgi M; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305., Cirrito JR; Department of Neurology, Washington University, St. Louis, MO 63110.; Knight Alzheimer's Disease Research Center, Washington University Medical Center, St. Louis, MO 63110.; Hope Center for Neurological Disorders, Washington University, St. Louis, MO 63110., Wyss-Coray T; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA 94305 twc@Stanford.edu.; Paul F. Glenn Center for the Biology of Aging, Stanford University School of Medicine, Stanford, CA 94305.; Center for Tissue Regeneration, Repair, and Restoration, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304.
Source: The Journal of experimental medicine [J Exp Med] 2017 Apr 03; Vol. 214 (4), pp. 1081-1092. Date of Electronic Publication: 2017 Mar 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985109R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-9538 (Electronic) Linking ISSN: 00221007 NLM ISO Abbreviation: J Exp Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1540-9538
DOI:10.1084/jem.20162011