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Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.

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Title: Absence of functional fetal regulatory T cells in humans causes in utero organ-specific autoimmunity.
Authors: Allenspach EJ; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Finn LS; Department of Laboratories, Seattle Children's Hospital, Seattle, Wash; Department of Pathology, University of Washington School of Medicine, Seattle, Wash., Rendi MH; Department of Pathology, University of Washington School of Medicine, Seattle, Wash., Eken A; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Singh AK; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Oukka M; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Taylor SD; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Altman MC; Benaroya Research Institute, Seattle, Wash; Department of Medicine, University of Washington School of Medicine, Seattle, Wash., Fligner CL; Department of Pathology, University of Washington School of Medicine, Seattle, Wash; Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, Wash., Ochs HD; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Rawlings DJ; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash., Torgerson TR; Department of Pediatrics, University of Washington School of Medicine, Seattle, Wash; Center for Immunity and Immunotherapies, Seattle Children's Research Institute, Seattle, Wash. Electronic address: troy.torgerson@seattlechildrens.org.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2017 Aug; Vol. 140 (2), pp. 616-619.e7. Date of Electronic Publication: 2017 Mar 16.
Publication Type: Case Reports; Letter; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-6825
DOI:10.1016/j.jaci.2017.02.017