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Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin.

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Title: Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin.
Authors: Tang SC; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan; Department of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan., Liao PY; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan., Hung SJ; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan., Ge JS; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan., Chen SM; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan., Lai JC; Research Assistant Center, Chang Hua Show Chwan Health, Care System, Changhua 50008, Taiwan., Hsiao YP; Institute of Medicine, School of Medicine, Chung Shan Medical University, Taichung 40244, Taiwan; Department of Dermatology, Chung Shan Medical University Hospital, Taichung 40244, Taiwan., Yang JH; Department of Dermatology, Buddhist Tzu Chi General Hospital, Hualien 97004, Taiwan; Department of Biochemistry, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan; Institute of Medicine, School of Medicine, Tzu Chi University, Hualien 97004, Taiwan. Electronic address: jh.med.edu@gms.tcu.edu.tw.
Source: Journal of dermatological science [J Dermatol Sci] 2017 Jun; Vol. 86 (3), pp. 238-248. Date of Electronic Publication: 2017 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 9011485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-569X (Electronic) Linking ISSN: 09231811 NLM ISO Abbreviation: J Dermatol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-569X
DOI:10.1016/j.jdermsci.2017.03.004