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Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

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Title: Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.
Authors: Pulley JM; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee., Shirey-Rice JK; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee., Lavieri RR; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee., Jerome RN; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee., Zaleski NM; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee., Aronoff DM; 2 Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine , Nashville, Tennessee.; 3 Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee., Bastarache L; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee., Niu X; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee., Holroyd KJ; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 5 Center for Technology Transfer and Commercialization, Vanderbilt University , Nashville, Tennessee., Roden DM; 6 Office of Research, Vanderbilt University Medical Center , Nashville, Tennessee., Skaar EP; 7 Department of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University School of Medicine , Nashville, Tennessee., Niswender CM; 8 Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center , Nashville, Tennessee.; 9 Vanderbilt Kennedy University Center for Excellence in Development Disabilities, Nashville, Tennessee., Marnett LJ; 10 Department of Chemistry, Vanderbilt University , Nashville, Tennessee.; 11 Department of Biochemistry, Vanderbilt University Medical School , Nashville Tennessee., Lindsley CW; 10 Department of Chemistry, Vanderbilt University , Nashville, Tennessee.; 12 Department of Medicinal Chemistry, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center , Nashville, Tennessee., Ekstrom LB; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 13 Nashville Biosciences, Nashville, Tennessee., Bentley AR; 5 Center for Technology Transfer and Commercialization, Vanderbilt University , Nashville, Tennessee., Bernard GR; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 6 Office of Research, Vanderbilt University Medical Center , Nashville, Tennessee., Hong CC; 14 Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine , Nashville, Tennessee.; 15 Department of Cell and Developmental Biology, Vanderbilt University School of Medicine , Nashville, Tennessee., Denny JC; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee.
Source: Assay and drug development technologies [Assay Drug Dev Technol] 2017 Apr; Vol. 15 (3), pp. 113-119. Date of Electronic Publication: 2017 Apr 05.
Publication Type: Journal Article; Technical Report
Journal Info: Publisher: Mary Ann Liebert, Inc Country of Publication: United States NLM ID: 101151468 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-8127 (Electronic) Linking ISSN: 1540658X NLM ISO Abbreviation: Assay Drug Dev Technol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.
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  Data: <searchLink fieldCode="AU" term="%22Pulley+JM%22">Pulley JM</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Shirey-Rice+JK%22">Shirey-Rice JK</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Lavieri+RR%22">Lavieri RR</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Jerome+RN%22">Jerome RN</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Zaleski+NM%22">Zaleski NM</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Aronoff+DM%22">Aronoff DM</searchLink>; 2 Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine , Nashville, Tennessee.; 3 Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Bastarache+L%22">Bastarache L</searchLink>; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Niu+X%22">Niu X</searchLink>; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Holroyd+KJ%22">Holroyd KJ</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 5 Center for Technology Transfer and Commercialization, Vanderbilt University , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Roden+DM%22">Roden DM</searchLink>; 6 Office of Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Skaar+EP%22">Skaar EP</searchLink>; 7 Department of Pathology, Microbiology, and Immunology, Division of Molecular Pathogenesis, Vanderbilt University School of Medicine , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Niswender+CM%22">Niswender CM</searchLink>; 8 Department of Pharmacology, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center , Nashville, Tennessee.; 9 Vanderbilt Kennedy University Center for Excellence in Development Disabilities, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Marnett+LJ%22">Marnett LJ</searchLink>; 10 Department of Chemistry, Vanderbilt University , Nashville, Tennessee.; 11 Department of Biochemistry, Vanderbilt University Medical School , Nashville Tennessee.<br /><searchLink fieldCode="AU" term="%22Lindsley+CW%22">Lindsley CW</searchLink>; 10 Department of Chemistry, Vanderbilt University , Nashville, Tennessee.; 12 Department of Medicinal Chemistry, Vanderbilt Center for Neuroscience Drug Discovery, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Ekstrom+LB%22">Ekstrom LB</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 13 Nashville Biosciences, Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Bentley+AR%22">Bentley AR</searchLink>; 5 Center for Technology Transfer and Commercialization, Vanderbilt University , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Bernard+GR%22">Bernard GR</searchLink>; 1 Vanderbilt Institute for Clinical and Translational Research, Vanderbilt University Medical Center , Nashville, Tennessee.; 6 Office of Research, Vanderbilt University Medical Center , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Hong+CC%22">Hong CC</searchLink>; 14 Department of Medicine, Division of Cardiovascular Medicine, Vanderbilt University School of Medicine , Nashville, Tennessee.; 15 Department of Cell and Developmental Biology, Vanderbilt University School of Medicine , Nashville, Tennessee.<br /><searchLink fieldCode="AU" term="%22Denny+JC%22">Denny JC</searchLink>; 4 Department of Biomedical Informatics, Vanderbilt University School of Medicine , Nashville, Tennessee.
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  Data: <searchLink fieldCode="JN" term="%22101151468%22">Assay and drug development technologies</searchLink> [Assay Drug Dev Technol] 2017 Apr; Vol. 15 (3), pp. 113-119. <i>Date of Electronic Publication: </i>2017 Apr 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Mary+Ann+Liebert%2C+Inc%22">Mary Ann Liebert, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101151468 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-8127 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221540658X%22">1540658X </searchLink><i>NLM ISO Abbreviation: </i>Assay Drug Dev Technol <i>Subsets: </i>MEDLINE
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        Value: 10.1089/adt.2016.772
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        Text: English
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