Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes.

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Title: Use of short interfering RNA delivered by cationic liposomes to enable efficient down-regulation of PTPN22 gene in human T lymphocytes.
Authors: Perri V; Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy., Pellegrino M; Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy., Ceccacci F; CNR Chemical Methodologies Institute-Section Mechanisms of reaction (CNR-IMC-SMR) c/o Sapienza University, Rome, Italy., Scipioni A; Department of Chemistry, Sapienza University, Rome, Italy., Petrini S; Confocal Microscopy Core Facility, Research Laboratories, Children's Hospital Bambino Gesù, Rome, Italy., Gianchecchi E; Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy., Lo Russo A; Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy., De Santis S; Department of Chemistry, Sapienza University, Rome, Italy., Mancini G; CNR Chemical Methodologies Institute (CNR-IMC), Rome, Italy., Fierabracci A; Type 1 Diabetes Centre, Infectivology and Clinical Trials Area, Children's Hospital Bambino Gesù, Rome, Italy.
Source: PloS one [PLoS One] 2017 Apr 24; Vol. 12 (4), pp. e0175784. Date of Electronic Publication: 2017 Apr 24 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1932-6203
DOI:10.1371/journal.pone.0175784