Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells.

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Title: Translation, but not transfection limits clinically relevant, exogenous mRNA based induction of alpha-4 integrin expression on human mesenchymal stem cells.
Authors: Nowakowski A; NeuroRepair Department, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland., Andrzejewska A; NeuroRepair Department, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland., Boltze J; Fraunhofer-Institute for Cell Therapy and Immunology, Department of Cell Therapy, University of Leipzig, Leipzig, Germany.; Translational Centre for Regenerative Medicine, University of Leipzig, Leipzig, Germany.; Fraunhofer Research Institution of Marine Biotechnology, Department of Translational Medicine and Cell Technology, Lübeck, Germany.; Institute for Medical and Marine Biotechnology, University of Lübeck, Lübeck, Germany., Nitzsche F; Fraunhofer-Institute for Cell Therapy and Immunology, Department of Cell Therapy, University of Leipzig, Leipzig, Germany.; Translational Centre for Regenerative Medicine, University of Leipzig, Leipzig, Germany., Cui LL; Stroke Recovery Laboratory, Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland., Jolkkonen J; Stroke Recovery Laboratory, Institute of Clinical Medicine - Neurology, University of Eastern Finland, Kuopio, Finland.; Neurocenter, Neurology, University Hospital of Kuopio, Kuopio, Finland., Walczak P; Russell H. Morgan Dept. of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, USA.; Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, USA.; Department of Neurology and Neurosurgery, Faculty of Medical Sciences, University of Warmia and Mazury, Olsztyn, Poland., Lukomska B; NeuroRepair Department, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland., Janowski M; NeuroRepair Department, Mossakowski Medical Research Centre, Polish Academy of Sciences, Warsaw, Poland. mjanows1@jhmi.edu.; Russell H. Morgan Dept. of Radiology and Radiological Science, Division of MR Research, The Johns Hopkins University School of Medicine, Baltimore, USA. mjanows1@jhmi.edu.; Institute for Cell Engineering, The Johns Hopkins University School of Medicine, Baltimore, USA. mjanows1@jhmi.edu.
Source: Scientific reports [Sci Rep] 2017 Apr 24; Vol. 7 (1), pp. 1103. Date of Electronic Publication: 2017 Apr 24.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2045-2322
DOI:10.1038/s41598-017-01304-3