Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury.
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| Title: | Test systems in drug discovery for hazard identification and risk assessment of human drug-induced liver injury. |
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| Authors: | Weaver RJ; a Research & Biopharmacy, Institut de Recherches Internationales Servier , Suresnes , France., Betts C; b Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK., Blomme EAG; c Preclinical Safety , AbbVie , North Chicago , USA., Gerets HHJ; d Non Clinical Development, Chemin du Foriest , UCB BioPharma SPRL , Braine L'Alleud , Belgium., Gjervig Jensen K; e Drug ADME Research, H. Lundbeck A/S , 9 Ottiliavej , Valby , Denmark., Hewitt PG; f Non-Clinical Development, Merck KGaA , Darmstadt , Germany., Juhila S; g In Vitro Biology , Orion Pharma , Espoo , Finland., Labbe G; h Investigative Toxicology, Preclinical Safety , Sanofi R&D , Paris , France., Liguori MJ; c Preclinical Safety , AbbVie , North Chicago , USA., Mesens N; i Preclinical Development & Safety, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium., Ogese MO; j Pathology Sciences, Drug Safety and Metabolism , AstraZeneca R&D , Cambridge , UK., Persson M; k Innovative Medicines and Early Clinical Development, Drug Safety and Metabolism, Discovery Safety , AstraZeneca R&D , Mölndal , Sweden., Snoeys J; l Pharmacokinetics Dynamics & Metabolism, Janssen (Pharmaceutical Companies of Johnson & Johnson) Turnhoutseweg 30 , Beerse , Belgium., Stevens JL; m Dept of Toxicology , Lilly Research Laboratories, Eli Lilly and Company , Indianapolis , Indiana , USA., Walker T; n Investigative Safety & Drug Metabolism , GlaxoSmithKline, David Jack Centre for Research and Development , Ware , Herts , Hertfordshire, UK., Park BK; o Institute of Translational Medicine , University of Liverpool , Liverpool , UK. |
| Source: | Expert opinion on drug metabolism & toxicology [Expert Opin Drug Metab Toxicol] 2017 Jul; Vol. 13 (7), pp. 767-782. Date of Electronic Publication: 2017 Jun 28. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Informa Healthcare Country of Publication: England NLM ID: 101228422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7607 (Electronic) Linking ISSN: 17425255 NLM ISO Abbreviation: Expert Opin Drug Metab Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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