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TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.

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Title: TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis.
Authors: Cammareri P; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Vincent DF; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Hodder MC; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Ridgway RA; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Murgia C; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Nobis M; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Campbell AD; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Varga J; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt 60596 Germany., Huels DJ; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Subramani C; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Prescott KLH; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Nixon C; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Hedley A; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK., Barry ST; Oncology IMED, AstraZeneca, Alderley Park SK10 4TG, Cambridge, UK., Greten FR; Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus, Frankfurt 60596 Germany.; German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg 69120, Germany., Inman GJ; Division of Cancer Research, School of Medicine, University of Dundee, Dundee DD1 9SY, UK., Sansom OJ; Wnt Signaling and Colorectal Cancer Group, Cancer Research UK Beatson Institute, Garscube Estate, Glasgow G61 1BD, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow G61 1QH, UK.
Source: Cell death and differentiation [Cell Death Differ] 2017 Oct; Vol. 24 (10), pp. 1681-1693. Date of Electronic Publication: 2017 Jun 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9437445 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5403 (Electronic) Linking ISSN: 13509047 NLM ISO Abbreviation: Cell Death Differ Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5403
DOI:10.1038/cdd.2017.92