Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
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| Title: | Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes. |
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| Authors: | Ruhrmann S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Ewing E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Piket E; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Kular L; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Cetrulo Lorenzi JC; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Department of Genetics, Medical School of Ribeirão Preto, São Paulo University, Ribeirão Preto, Brazil., Fernandes SJ; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden., Morikawa H; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden., Aeinehband S; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Sayols-Baixeras S; Cardiovascular Epidemiology and Genetics Group, Institut Hospital del Mar d'Investigacions Mediques (IMIM), Barcelona, Spain/ Universitat Pompeu Fabra (UPF), Barcelona, Spain., Aslibekyan S; Department of Epidemiology, University of Alabama at Birmingham, Birmingham, AL, USA., Absher DM; HudsonAlpha Institute for Biotechnology, Huntsville, AL, USA., Arnett DK; College of Public Health, University of Kentucky, Lexington, KY, USA., Tegner J; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Science for Life Laboratory, Stockholm, Sweden/ Biological and Environmental Sciences and Engineering Division, Computer, Electrical and Mathematical Sciences and Engineering Division, King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia., Gomez-Cabrero D; Unit of Computational Medicine, Department of Medicine, Solna, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden/ Mucosal & Salivary Biology Division, Dental Institute, King's College London, London, UK., Piehl F; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden., Jagodic M; Department of Clinical Neuroscience, Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden. |
| Source: | Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2018 Sep; Vol. 24 (10), pp. 1288-1300. Date of Electronic Publication: 2017 Aug 02. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: SAGE Publications Country of Publication: England NLM ID: 9509185 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-0970 (Electronic) Linking ISSN: 13524585 NLM ISO Abbreviation: Mult Scler Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1477-0970 |
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| DOI: | 10.1177/1352458517721356 |
