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Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.

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Bibliographic Details
Title: Lung tumors with distinct p53 mutations respond similarly to p53 targeted therapy but exhibit genotype-specific statin sensitivity.
Authors: Turrell FK; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Kerr EM; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Gao M; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Thorpe H; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Doherty GJ; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom.; Department of Oncology, Addenbrooke's Hospital, Cambridge, CB2 0QQ, United Kingdom., Cridge J; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Shorthouse D; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Speed A; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Samarajiwa S; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Hall BA; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom., Griffiths M; Department of Histopathology, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge, CB2 0QQ, United Kingdom., Martins CP; Medical Research Council (MRC) Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge CB2 0XZ, United Kingdom.
Source: Genes & development [Genes Dev] 2017 Jul 01; Vol. 31 (13), pp. 1339-1353. Date of Electronic Publication: 2017 Aug 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1549-5477
DOI:10.1101/gad.298463.117