Gemcitabine combined with the monoclonal antibody nimotuzumab is an active first-line regimen in KRAS wildtype patients with locally advanced or metastatic pancreatic cancer: a multicenter, randomized phase IIb study.

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Title: Gemcitabine combined with the monoclonal antibody nimotuzumab is an active first-line regimen in KRAS wildtype patients with locally advanced or metastatic pancreatic cancer: a multicenter, randomized phase IIb study.
Authors: Schultheis B; Department of Hematology/Oncology, University Bochum, Marien Hospital Herne, Herne;. Electronic address: beate.schultheis@elisabethgruppe.de., Reuter D; Oncoscience AG, Wedel (recently Schenefeld)., Ebert MP; Klinikum Rechts der Isar TU München, München., Siveke J; Klinikum Rechts der Isar TU München, München., Kerkhoff A; University Hospital Münster, Münster., Berdel WE; University Hospital Münster, Münster., Hofheinz R; Department of Hematology and Medical Oncology, University Medical Center Mannheim, Mannheim., Behringer DM; Augusta-Kranken-Anstalt, Bochum., Schmidt WE; St. Josef Hospital, Med. Klinik I, Bochum, Germany., Goker E; Ege University Medical School, Izmir, Turkey., De Dosso S; Oncology Institute of Southern Switzerland, Bellinzona, Switzerland., Kneba M; Department of Medicine, University Medical Center Schleswig-Holstein, Kiel, Germany., Yalcin S; Hacettepe University Hospital, Ankara, Turkey., Overkamp F; Medical Practice for Oncology and Hematology, Recklinghausen., Schlegel F; St. Antonius Hospital, Eschweiler., Dommach M; Sana-Kliniken, Medizinisches Versorgungszentrum Onkologie, Düsseldorf., Rohrberg R; Gemeinschaftspraxis und Tagesklinik fuer Haematologie, Onkologie und Gastroenterologie, Halle., Steinmetz T; Group Practice Hematology/Oncology Cologne, Cologne., Bulitta M; CRM Biometrics GmbH, Rheinbach, Germany., Strumberg D; Department of Hematology/Oncology, University Bochum, Marien Hospital Herne, Herne.
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2017 Oct 01; Vol. 28 (10), pp. 2429-2435.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1569-8041
DOI:10.1093/annonc/mdx343