Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.

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Title: Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.
Authors: de Groot JS; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., van Diest PJ; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., van Amersfoort M; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Vlug EJ; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Pan X; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Ter Hoeve ND; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands., Rosing H; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Beijnen JH; Department of Pharmacy and Pharmacology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Youssef SA; Department of Pathobiology, Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., de Bruin A; Department of Pathobiology, Dutch Molecular Pathology Center, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.; Department of Pediatrics, Division of Molecular Genetics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands., Jonkers J; Department of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., van der Wall E; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands., Derksen PWB; Department of Pathology, University Medical Center Utrecht, Utrecht, The Netherlands.
Source: Oncotarget [Oncotarget] 2017 Jun 15; Vol. 8 (37), pp. 60750-60763. Date of Electronic Publication: 2017 Jun 15 (Print Publication: 2017).
Publication Type: Journal Article
Journal Info: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: eCollection Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1949-2553
DOI:10.18632/oncotarget.18490