DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.

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Bibliographic Details
Title: DOCK8 enforces immunological tolerance by promoting IL-2 signaling and immune synapse formation in Tregs.
Authors: Janssen E; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Kumari S; Department of Bioengineering and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Tohme M; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Ullas S; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Barrera V; Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Tas JM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Castillo-Rama M; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA., Bronson RT; Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA., Usmani SM; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Irvine DJ; Department of Bioengineering and Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA., Mempel TR; Center for Immunology and Inflammatory Diseases, Massachusetts General Hospital, Boston, Massachusetts, USA; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Geha RS; Division of Immunology, Boston Children's Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Source: JCI insight [JCI Insight] 2017 Oct 05; Vol. 2 (19). Date of Electronic Publication: 2017 Oct 05.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight
Database: MEDLINE Ultimate
Description
ISSN:2379-3708
DOI:10.1172/jci.insight.94298