Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.
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| Title: | Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study. |
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| Authors: | Amare AT; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia., Schubert KO; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia.; Northern Adelaide Local Health Network, Mental Health Services, Adelaide, South Australia, Australia., Hou L; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland., Clark SR; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia., Papiol S; Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig-Maximilian University of Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University of Munich, Munich, Germany., Heilbronner U; Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig-Maximilian University of Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August University Göttingen, Göttingen, Germany., Degenhardt F; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Tekola-Ayele F; Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland., Hsu YH; Hebrew SeniorLife Institute for Aging Research, Harvard Medical School, Boston, Massachusetts.; Program for Quantitative Genomics, Harvard School of Public Health, Boston, Massachusetts.; Broad Institute of Massachusetts Institute of Technology and Harvard, Cambridge, Massachusetts., Shekhtman T; Department of Psychiatry, University of California San Diego., Adli M; Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany., Akula N; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland., Akiyama K; Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Mibu, Tochigi, Japan., Ardau R; Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy., Arias B; Unitat de Zoologia i Antropologia Biològica (Dpt Biologia Evolutiva, Ecologia i Ciències Ambientals), Facultat de Biologia and Institut de Biomedicina, University of Barcelona, Centro de Investigación Biomédica en Red de Salud Mental, Barcelona, Spain., Aubry JM; Department of Psychiatry, Mood Disorders Unit, Geneva University Hospitals, Geneva, Switzerland., Backlund L; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Bhattacharjee AK; Department of Psychiatry, University of California San Diego., Bellivier F; Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche Scientifique 1144, Université Paris Diderot, Département de Psychiatrie et de Médecine Addictologique, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F. Widal, Paris, France., Benabarre A; Bipolar Disorder Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red Salud Mental, Barcelona, Catalonia, Spain., Bengesser S; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Biernacka JM; Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota.; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota., Birner A; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Brichant-Petitjean C; Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche Scientifique 1144, Université Paris Diderot, Département de Psychiatrie et de Médecine Addictologique, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F. Widal, Paris, France., Cervantes P; The Neuromodulation Unit, McGill University Health Centre, Montreal, Canada., Chen HC; Department of Psychiatry and Center of Sleep Disorders, National Taiwan University Hospital, Taipei, Taiwan., Chillotti C; Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy., Cichon S; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland., Cruceanu C; Douglas Mental Health University Institute, McGill University, Montreal, Canada., Czerski PM; Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznan, Poland., Dalkner N; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Dayer A; Department of Psychiatry, Mood Disorders Unit, Geneva University Hospitals, Geneva, Switzerland., Del Zompo M; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., DePaulo JR; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland., Étain B; Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche Scientifique 1144, Université Paris Diderot, Département de Psychiatrie et de Médecine Addictologique, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Saint-Louis-Lariboisière-F. Widal, Paris, France., Falkai P; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian University of Munich, Munich, Germany., Forstner AJ; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Department of Psychiatry, University of Basel, Basel, Switzerland., Frisen L; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Frye MA; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minnesota., Fullerton JM; Neuroscience Research Australia, Sydney, New South Wales, Australia.; School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia., Gard S; Service de Psychiatrie, Hôpital Charles Perrens, Bordeaux, France., Garnham JS; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Goes FS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland., Grigoroiu-Serbanescu M; Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania., Grof P; Mood Disorders Center of Ottawa, Ontario, Canada., Hashimoto R; Molecular Research Center for Children's Mental Development, United Graduate School of Child Development, Osaka University, Osaka, Japan.; Department of Psychiatry, Osaka University Graduate School of Medicine, Osaka, Japan., Hauser J; Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznan, Poland., Herms S; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland., Hoffmann P; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany.; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland., Hofmann A; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Jamain S; Institut National de la Santé et de la Recherche Médicale Unité 955, Psychiatrie Translationnelle, Créteil, France., Jiménez E; Bipolar Disorder Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red Salud Mental, Barcelona, Catalonia, Spain., Kahn JP; Service de Psychiatrie et Psychologie Clinique, Centre Psychothérapique de Nancy, Université de Lorraine, Nancy, France., Kassem L; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland., Kuo PH; Department of Public Health and Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Kato T; Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Saitama, Japan., Kelsoe J; Department of Psychiatry, University of California San Diego., Kittel-Schneider S; Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Kliwicki S; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznan, Poland., König B; Department of Psychiatry and Psychotherapeutic Medicine, Landesklinikum Neunkirchen, Neunkirchen, Austria., Kusumi I; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan., Laje G; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland., Landén M; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the Gothenburg University, Gothenburg, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lavebratt C; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Leboyer M; Inserm U955, Translational Psychiatry Laboratory, Université Paris-Est-Créteil, Department of Psychiatry and Addictology of Mondor University Hospital, Assistance Publique-Hôpitaux de Paris, Hôpital Albert Chenevier-Henri Mondor, Pôle de Psychiatrie, Créteil, France., Leckband SG; Department of Pharmacy, Veterans Affairs San Diego Healthcare System, San Diego, California., Tortorella A; Department of Psychiatry, University of Perugia, Perugia, Italy., Manchia M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Nova Scotia, Canada., Martinsson L; Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden., McCarthy MJ; Department of Psychiatry, University of California San Diego.; Department of Psychiatry, Veterans Affairs San Diego Healthcare System, San Diego, California., McElroy S; Department of Psychiatry, Lindner Center of Hope and University of Cincinnati, Mason, Ohio., Colom F; Bipolar Disorder Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red Salud Mental, Barcelona, Catalonia, Spain.; Mental Health Research Group, IMIM-Hospital del Mar, Barcelona, Catalonia, Spain., Mitjans M; Centro de Investigación Biomédica en Red de Salud Mental, Instituto de Salud Carlos III, Madrid, Spain.; Clinical Neuroscience, Max Planck Institute of Experimental Medicine, Göttingen, Germany., Mondimore FM; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland., Monteleone P; Neurosciences Section, Department of Medicine and Surgery, University of Salerno, Salerno, Italy.; Department of Psychiatry, Second University of Naples, Naples, Italy., Nievergelt CM; Department of Psychiatry, University of California San Diego., Nöthen MM; Institute of Human Genetics and Department of Genomics, Life & Brain Center, University of Bonn, Bonn, Germany., Novák T; National Institute of Mental Health, Klecany, Czech Republic., O'Donovan C; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Ozaki N; Department of Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Ösby U; Department of Neurobiology, Care Sciences, and Society, Karolinska Institutet and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Pfennig A; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Germany., Potash JB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland., Reif A; Laboratory for Molecular Dynamics of Mental Disorders, RIKEN Brain Science Institute, Saitama, Japan., Reininghaus E; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Rouleau GA; Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada., Rybakowski JK; Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Schalling M; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Schofield PR; Neuroscience Research Australia, Sydney, New South Wales, Australia.; School of Medical Sciences, University of New South Wales, Sydney, New South Wales, Australia., Schweizer BW; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland., Severino G; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Shilling PD; Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden, and Center for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden., Shimoda K; Department of Psychiatry, Dokkyo University School of Medicine, Mibu, Tochigi, Japan., Simhandl C; Bipolar Center Wiener Neustadt, Sigmund Freud University, Medical Faculty, Vienna, Austria., Slaney CM; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Squassina A; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Stamm T; Department of Psychiatry and Psychotherapy, Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany., Stopkova P; National Institute of Mental Health, Klecany, Czech Republic., Maj M; Department of Psychiatry, Second University of Naples, Naples, Italy., Turecki G; Douglas Mental Health University Institute, McGill University, Montreal, Canada., Vieta E; Bipolar Disorder Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Centro de Investigación Biomédica en Red Salud Mental, Barcelona, Catalonia, Spain., Volkert J; Department of Psychiatry, Psychosomatic Medicine, and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Witt S; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Wright A; School of Psychiatry, University of New South Wales, and Black Dog Institute, Sydney, New South Wales, Australia., Zandi PP; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland., Mitchell PB; School of Psychiatry, University of New South Wales, and Black Dog Institute, Sydney, New South Wales, Australia., Bauer M; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Germany., Alda M; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., McMahon FJ; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland., Schulze TG; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health and Human Services, Bethesda, Maryland.; Institute of Psychiatric Phenomics and Genomics, University Hospital, Ludwig-Maximilian University of Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Medical Center, Georg-August University Göttingen, Göttingen, Germany.; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, Maryland.; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Baune BT; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, South Australia, Australia. |
| Corporate Authors: | International Consortium on Lithium Genetics (ConLi+Gen) |
| Source: | JAMA psychiatry [JAMA Psychiatry] 2018 Jan 01; Vol. 75 (1), pp. 65-74. |
| Publication Type: | Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Medical Association Country of Publication: United States NLM ID: 101589550 Publication Model: Print Cited Medium: Internet ISSN: 2168-6238 (Electronic) Linking ISSN: 2168622X NLM ISO Abbreviation: JAMA Psychiatry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2168-6238 |
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| DOI: | 10.1001/jamapsychiatry.2017.3433 |
