Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.

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Title: Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.
Authors: Zhang H; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Anesthesia, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310006, China., Zhao H; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China., Zeng C; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China., Van Dort C; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA; Picower Institute for Learning and Memory, MIT, Cambridge, MA 02139, USA., Faingold CL; Department of Pharmacology and Neurology, Division of Neurosurgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA., Taylor NE; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA., Solt K; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA., Feng HJ; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA. Electronic address: feng.huajun@mgh.harvard.edu.
Source: Neurobiology of disease [Neurobiol Dis] 2018 Feb; Vol. 110, pp. 47-58. Date of Electronic Publication: 2017 Nov 13.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 9500169 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-953X (Electronic) Linking ISSN: 09699961 NLM ISO Abbreviation: Neurobiol Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Optogenetic activation of 5-HT neurons in the dorsal raphe suppresses seizure-induced respiratory arrest and produces anticonvulsant effect in the DBA/1 mouse SUDEP model.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Anesthesia, Hangzhou First People's Hospital, Nanjing Medical University, Hangzhou 310006, China.<br /><searchLink fieldCode="AU" term="%22Zhao+H%22">Zhao H</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.<br /><searchLink fieldCode="AU" term="%22Zeng+C%22">Zeng C</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Health Management Center, Xiangya Hospital, Central South University, Changsha 410008, China.<br /><searchLink fieldCode="AU" term="%22Van+Dort+C%22">Van Dort C</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA; Department of Brain and Cognitive Sciences, MIT, Cambridge, MA 02139, USA; Picower Institute for Learning and Memory, MIT, Cambridge, MA 02139, USA.<br /><searchLink fieldCode="AU" term="%22Faingold+CL%22">Faingold CL</searchLink>; Department of Pharmacology and Neurology, Division of Neurosurgery, Southern Illinois University School of Medicine, Springfield, IL 62794, USA.<br /><searchLink fieldCode="AU" term="%22Taylor+NE%22">Taylor NE</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Solt+K%22">Solt K</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA.<br /><searchLink fieldCode="AU" term="%22Feng+HJ%22">Feng HJ</searchLink>; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Department of Anesthesia, Harvard Medical School, Boston, MA 02114, USA. Electronic address: feng.huajun@mgh.harvard.edu.
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  Data: <searchLink fieldCode="JN" term="%229500169%22">Neurobiology of disease</searchLink> [Neurobiol Dis] 2018 Feb; Vol. 110, pp. 47-58. <i>Date of Electronic Publication: </i>2017 Nov 13.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9500169 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-953X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209699961%22">09699961 </searchLink><i>NLM ISO Abbreviation: </i>Neurobiol Dis <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.nbd.2017.11.003
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              Text: 2018 Feb
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              Y: 2018
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